If your horses are on other glucosamine and chondroitin supplements you do not need them when on RR…..RR contains smaller doses but they are much more effective than large doses of these products. Although we mention vitamins in Rapid Response, they are from natural sources and do not contain all your horse needs and thus I would recommend a vitamin and mineral supplement. If you check out our mineral, vitamin and antioxidant Total Effort (out of stock at this time) formula is complete. All of our products were formulated by Dr. Fourziano to be used together. The UnTyeMe formula contains good sources of Vitamin E, Selenium and Magnesium for muscles. UnTyeMe is an excellent source of selenium in areas where the soil and also the hay grown on that soil is depleted of selenium!! Full Energyis an excellent protein source and promotes excellent coat and hoof growth.